微生物学评论对无症状细菌尿症的管理的影响
Bitalio Jhon Montaño-Barrientos1, María Teresa Pérez-Rodríguez2, Sonia María Rey-Cao1
1Department of Microbiology, Complexo Hospitalario Universitario de Vigo, Vigo, Spain.
Antimicrobial stewardship & healthcare epidemiology : ASHE
|October 23, 2025
概括
将建议添加到微生物学报告中减少了对无症状细菌性尿症 (AB) 的抗生素处方. 这种干预有助于优化抗生素的使用和改善尿液培养管理,打击抗生素耐药性.
科学领域:
- 微生物学 微生物学
- 传染性疾病 传染性疾病
- 临床药房 临床药房
背景情况:
- 无症状细菌尿症 (AB) 的治疗与抗生素耐药性增加和Clostridioides difficile感染有关.
- 目前针对AB的管理策略缺乏明确的临床益处,并导致过度使用抗微生物药物.
研究的目的:
- 评估在微生物学报告中包括关于对AB的抗生素处方的具体建议的影响.
- 评估旨在优化对无症状细菌的抗生素处方的干预措施的有效性.
主要方法:
- 确定了潜在的AB病例,并为微生物学报告添加了评论:"根据临床发现进行评估. 在AB中,不建议进行任何治疗.
- 收集关于患者人口统计,样本特征,测试原因,微生物发现,耐药性模式和治疗开始的数据.
- 分析了与遵守和不遵守微生物学建议相关的因素.
主要成果:
- 在391例确诊病例中,60%的病例开始接受抗生素治疗.
- 只有40%的病例遵循了不治疗AB的微生物建议.
- 不坚持与针对非特异性症状 (例如,阴或恶臭的尿液) 要求的尿液培养和重复培养有关;坚持对于例行健康检查培养更高.
结论:
- 将评论纳入微生物学报告可以减少对AB的抗菌素处方.
- 这种干预措施显示了优化抗生素处方和改善尿液培养请求管理政策的潜力.
- 这些发现表明,可以采取一种实际的方法来减少无症状细菌尿症中不必要的抗生素使用.
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