在胃肠道病原体小组结果呈阳性后,对疑似传染性腹进行了抗菌变化
Natalie A Mackow1,2, Madison G Ponder3, Samantha R Eiffert4
1Division of Infectious Diseases, Department of Medicine, University of North Carolina School of Medicine, Chapel Hill, NC, USA.
Antimicrobial stewardship & healthcare epidemiology : ASHE
|October 23, 2025
概括
在37%的患者中,抗菌药物管理发生了变化,这些患者的胃肠道病原体多重组 (GIP) 结果呈阳性,大多数变化都遵守了指南. 经验治疗和门诊测试预测了这些抗微生物药物管理变化.
科学领域:
- 传染性疾病 传染性疾病
- 微生物学 微生物学
- 临床医学 临床医学
背景情况:
- 感染性腹的诊断依赖于识别引起病原体.
- 多重面板加快病原体检测,但需要适当的抗菌管理.
- 了解GIP测试后的抗菌管理变化对于优化治疗至关重要.
研究的目的:
- 确定在胃肠道病原体多重组 (GIP) 结果呈阳性后,抗微生物管理变化的频率.
- 为了确定与抗微生物治疗修改相关的预测因素.
- 评估这些变化是否符合临床指南.
主要方法:
- 在高等推中心进行回顾性队列研究.
- 包括腹和GIP阳性结果的成人和儿科患者.
- 分析了使用后勤回归的抗微生物管理变化和准则遵守情况.
主要成果:
- 在193名GIP阳性患者中,有71人 (37%) 改变了抗菌药物管理.
- 大多数变化 (86%) 是符合指南的.
- 经验性抗微生物治疗和门诊检测是管理变化的预测因素.
结论:
- 大约三分之一的GIP测试阳性患者经历了抗菌药物管理变化.
- 这些抗微生物药物管理变化中的大多数是符合指南的.
- 大多数积极的GIP结果不需要抗菌药物治疗.
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