帕克斯洛维德的使用和社会脆弱性:2022年至2023年康涅狄格州的趋势
Laura Hohenstein1, Meghan Maloney2, David B Banach1
1University of Connecticut School of Medicine, Farmington, CT, USA.
脆弱的社区面临着更大的COVID-19影响. 尽管帕克斯洛维德可用,但在社会脆弱性指数 (SVI) 高的地区,利用率较低,这突显了流行病准备的获取差异.
科学领域:
- 公共卫生 公共卫生
- 传染病流行病学 传染病流行病学
- 健康 公平 卫生 公平
背景情况:
- COVID-19 流行病加剧了现有的健康差异.
- 弱势群体经历了不成比例的严重影响.
- 公平获得抗病毒疗法对于抗击流行病的反应至关重要.
研究的目的:
- 评估社会脆弱性指数 (SVI) 和帕克斯洛维德发行地点的可访问性之间的关系.
- 调查与社区脆弱性相关的Paxlovid使用模式.
- 为公平的药物获取提供信息,为流行病准备战略提供信息.
主要方法:
- 地理空间分析比较人口普查区的SVI分数,其中有和没有Paxlovid发放地点.
- 对不同SVI水平的Paxlovid利用率的统计分析.
- 追溯队列研究设计.
主要成果:
- 与没有 (0.45,P <.01) 的人口普查区域相比,Paxlovid发放地点的SVI得分显著更高 (0.56),比没有 (0.45,P <.01).
- 帕克斯洛维德的利用与SVI相反相关,在高SVI区域的吸收较低.
- 在脆弱的社区中,获得抗病毒治疗的差异很明显.
结论:
- 疫情防控计划必须优先考虑公平分配和获得像Paxlovid这样的抗感染疗法.
- 解决社会脆弱性对于减轻公共卫生危机期间的健康差异至关重要.
- 未来的战略应侧重于克服贫困人口的抗病毒药物获取障碍.
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