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评估在门诊护理环境中出现肺栓塞的患者的发病和恶性瘤风险
Muhammed Memon1,2, Eram Anwar3,2, Kamran Shakir1,2
1Department of Acute Medicine, University Hospitals of Derby and Burton, Burton-on-Trent, United Kingdom.
Sultan Qaboos University medical journal
|October 23, 2025
概括
肺栓塞 (PE) 的门诊治疗是可行的. 简化肺栓塞严重性指数 (sPESI) 有助于风险分层,并识别患有新癌症部位 (NCS) 高风险的患者.
科学领域:
- 心脏病学 心脏病学
- 在瘤学瘤学.
- 紧急医疗 紧急医疗
背景情况:
- 静脉血栓栓塞 (VTE),特别是肺栓塞 (PE),可以在门诊环境中进行风险评估.
- 医生的不情愿和与癌症相关的静脉动脉瘤的复杂性可能会阻碍门诊PE管理.
- 早期发现新的癌症部位 (NCS) 在PE患者中至关重要.
研究的目的:
- 评估在急性医学门诊管理的PE患者的发病率和死亡率.
- 评估风险分层在门诊PE管理中的有效性.
- 在PE患者中识别新的癌症部位 (NCS).
主要方法:
- 在急性医学门诊机构 (2019-2022) 管理的82名确诊PE患者的回顾性研究 (2019-2022).
- 收集的数据包括生物化学和放射学发现,死亡/发病率,治疗方法,简化肺栓塞严重性指数 (sPESI) 评分,并发症和NCS诊断.
- 统计分析包括后勤回归和分类树方法.
主要成果:
- 增加的sPESI分数与较高的死亡率相关 (sPESI 0:0%死亡率;sPESI 3:50%在90天内死亡率).
- 在13.4%的患者中诊断出新的癌症部位 (NCS).
- 一个分类树模型预测NCS具有70.6%的灵敏度和97%的特异性,使用癌症史和年龄>73岁.
结论:
- 在风险分层的PE患者中,sPESI对具有不良结果的PE患者有价值.
- 分类树方法有效地识别了患有NCS发展高风险的患者.
- PE的门诊治疗得到了风险分层工具的支持,用于结局和癌症检测.
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