不同体力活动干预措施对老年痴呆症患者执行功能的影响:系统性审查和网络元分析
Ying Zhu1, Shuang Li1, Zixian Xiao2
1School of Physical Education and Health, Guangxi Normal University, Guilin, China.
Frontiers in neurology
|October 23, 2025
概括
抵抗运动和心身运动显示出改善痴呆症患者执行功能的前景. 本系统性审查对身体活动干预措施进行了排名,以指导老年痴呆症患者的有效治疗策略.
科学领域:
- 老年学是指老年学的学科.
- 神经科学是一个神经科学.
- 康复医学 康复医学 康复医学
背景情况:
- 执行功能障碍对患有痴呆症的老年人有重大影响.
- 身体活动被认为是增强这一群体认知功能的补充方法.
- 需要对痴呆症最有效的体育活动干预措施有系统的证据.
研究的目的:
- 系统地评估和排名体育活动干预措施,以改善老年痴呆症患者的执行功能.
- 为痴呆症护理提供治疗指导.
主要方法:
- 在PubMed,Cochrane图书馆,Embase和Web of Science数据库中进行系统搜索 (2000年1月至2025年5月).
- 包括随机对照试验 (RCT) 关于痴呆症中的身体活动和执行功能.
- 使用Stata 15.1.1.进行网络元分析.
主要成果:
- 分析了24项研究.
- 抵抗运动在增强执行功能方面排名最高 (SUCRA: 89.2%).
- 然后是心身运动 (SUCRA: 71.4%) 和有氧运动 (SUCRA: 60.0%).
结论:
- 抵抗和心身运动似乎是增强痴呆症执行功能的最有效方法.
- 未来的研究应该专注于个性化计划和调查干预机制 (例如神经营养因素,前额叶皮层连接性).
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