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用低度腹腔透析溶液复杂化的Bailing囊对患有慢性功能衰竭的腹腔透析患者的残留功能和微炎症状况的影响

Xiancheng Li¹, Yafeng Zhao¹, Xiaoyong Yu¹

¹Second Department of Nephrology, Shaanxi Provincial Hospital of Chinese Medicine, Xi'an, Shaanxi, China.

Frontiers in endocrinology

|October 23, 2025

概括

保释囊 (BLC) 与低腹腔透析溶液 (PDS) 结合,有效治疗经过腹腔透析 (PD) 的慢性功能衰竭 (CRF) 患者. 这种组合减缓了残留功能 (RRF) 衰退,并改善了患者的健康标志物,而不会增加不良影响.

科学领域:

腎臟病學 (nephrology) 是一種醫學專業.
药理学药理学是指药理学的学科.
生物化学生物化学

背景情况:

慢性功能衰竭 (CRF) 对接受腹腔透析 (PD) 的患者构成重大挑战.
维持残留功能 (RRF) 和管理炎症和氧化应激等并发症在PD管理中至关重要.
保释囊 (BLC) 是一种具有潜在治疗益处的传统中医药制剂.

研究的目的:

为了评估结合Bailing囊 (BLC) 与低腹膜透析溶液 (PDS) 的疗效和安全性,在患有CRF的PD患者中.
评估这种联合治疗对RRF,炎症,营养状况和氧化应激的影响.

主要方法:

一项随机对照试验涉及92名患有CRF的PD患者.
患者被分配到对照组 (低PDS,低蛋白饮食,α-ketoacid片) 或研究组 (BLC添加到对照方案).
测量结果包括临床疗效,RRF,炎症标志物 (TNF-α,CRP,IL-6),营养标志物 (前专辑蛋白,专辑蛋白,转激素,血红蛋白),氧化应激标志物 (MDA,SOD,GPx) 和不良反应.

主要成果:

与对照组相比,研究组的总有效率明显高 (P < 0.05).
在治疗后,研究小组的RRF下降速度较慢,炎症标志物减少,营养状况改善,氧化应激参数更好 (P<0.05).
两组之间没有观察到不良反应发生率的显著差异 (P > 0.05).

结论:

将BLC与低PDS结合起来,是患有CRF的PD患者的有效治疗策略.
这种组合疗法有助于保护RRF,减轻微炎症,改善营养状况,并管理氧化应激.
该治疗方案表现出有利的安全性,与传统治疗相美.

关键词:

一个保释囊.慢性功能衰竭慢性功能衰竭低的腹膜透析溶液.这是微炎症状态.腹膜透析是指腹膜透析.其余的功能.

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