缺铁性贫血与严重月经出血的青少年的抑郁症状有关
Ramya Ramakrishnan1, Hansa Boddu2, Kaleigh Riggs-Harpur3
1Department of Pediatrics, The University of Texas Health Science Center at Houston, MD Anderson Cancer Center, Houston, , Texas, USA.
Research and practice in thrombosis and haemostasis
|October 23, 2025
概括
严重的月经出血 (HMB) 与青少年的铁缺乏症 (ID) 和贫血 (IDA) 有关. 这项研究发现,改善HMB和IDA青少年的血红蛋白水平显著降低了抑郁症状.
科学领域:
- 青少年健康 青少年健康
- 血液学 血液学 血液学
- 心理健康 心理健康
背景情况:
- 严重的月经出血 (HMB) 和相关的缺铁 (ID) 有或没有贫血 (IDA) 负面影响青少年的健康.
- 缺铁和贫血是青少年HMB的常见并发症,导致各种不良健康结果.
研究的目的:
- 为了评估铁缺乏/贫血和患有HMB的青少年抑郁症状之间的关联.
- 为了评估铁缺乏和贫血对抑郁症状的影响,使用患者健康问卷 (PHQ) -9得分.
主要方法:
- 一个单一中心的回顾性记录审查对有记录的HMB和至少一个PHQ-9分数的青少年进行.
- 铁缺乏症被定义为铁素<25 ng/dL,而缺铁性贫血被定义为血红蛋白<12 g/dL.
- 统计模型被用来比较患有和没有ID/IDA的患者的PHQ-9分数,无论是横截面还是纵横.
主要成果:
- 51%的IDA青少年和37%的ID青少年在基线时呈现PHQ-9分数≥10.
- 抑郁症状 (PHQ-9分数) 随着血红蛋白水平的增加显著改善 (P = .04).
- HMB的改善与抑郁症状的减少相关,无论血红蛋白或费里水平 (P = .003).
结论:
- 解决和管理抑郁症状对于患有HMB和相关的缺铁性贫血的青少年至关重要.
- 这些发现强调了HMB青少年血液状况和精神健康之间的联系.
- 优化HMB和相关的IDA的管理可以带来更好的心理健康结果.
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