多功能HBc病毒样粒子重编程免疫抑制巨细胞,并增强CD8+T细胞反应,以增强癌症免疫疗法

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Updated: Jan 14, 2026

Generation of Multivirus-specific T Cells to Prevent/treat Viral Infections after Allogeneic Hematopoietic Stem Cell Transplant
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Generation of Multivirus-specific T Cells to Prevent/treat Viral Infections after Allogeneic Hematopoietic Stem Cell Transplant

Published on: May 27, 2011

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Shuntao Liang1, Xiaoxuan Yin1, Yongjie Chi2,3

  • 1Biomedical Innovation Center, Beijing Shijitan Hospital, Capital Medical University, Beijing, 100038, People's Republic of China.

International journal of nanomedicine
|October 23, 2025
PubMed
概括

这项研究引入了一种新型纳米疫苗,该疫苗可以重新编程免疫抑制性瘤相关巨细胞 (TAMs),并阻止B7-H3检查点. 这种方法在临床前模型中增强了抗瘤免疫力和免疫治疗疗效.

关键词:
封锁B7-H3检查站的封锁HBc VLP 在线播放在TAM重编程过程中.纳米疫苗的使用方法瘤免疫的微环境

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