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Updated: Jan 14, 2026

Yeast As a Chassis for Developing Functional Assays to Study Human P53
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在非小细胞肺癌中TP53功能增益突变的分子特征和治疗影响

Zheng Zhao1, Rui Lu2, Feng Zhang3

  • 1Department of Clinical Oncology, Shaanxi Provincial Cancer Hospital, Xi'an, China.

Cancer medicine
|October 23, 2025
PubMed
概括

在非小细胞肺癌 (NSCLC) 中TP53功能增益 (GOF) 突变与不同的分子配置和免疫活性有关. 这些突变预测ROS1-TKI治疗的结果较差,但对免疫治疗的反应有所改善.

关键词:
TP53功能的增益-功能增益.免疫疗法 免疫疗法这是下一代测序.非小细胞肺癌的肺癌.幸存率 幸存率 生存率

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