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Solid Phase Synthesis of a Functionalized Bis-Peptide Using "Safety Catch" Methodology
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开发ArgTag用于聚合的可扩展固体相合成

Vincent Freiburghaus1, Aliénor Jeandin1, Łukasz Frankiewicz2

  • 1Department of Chemistry, University of Zurich, Winterthurerstrasse 190, 8057 Zurich, Switzerland.

ACS chemical biology
|October 23, 2025
PubMed
概括

一个新的六氨酸标签 (ArgTag) 通过防止固相合成 (SPPS) 期间的聚合来简化合成. 这种方法提高了的纯度,并且在各种树脂和更大的尺度上有效.

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