呼吸系统病毒活动和季节性恢复到流行前的模式
Rainer Gosert1, Klaudia Naegele1, Marvin Weiss2
1Clinical Virology, University Hospital Basel, Basel, Switzerland.
Journal of medical virology
|October 23, 2025
概括
随着COVID-19大流行,呼吸系统病毒季节发生了变化,导致病毒数量下降,然后升,特别是在儿童中. 疫情后,病毒的季节性正在回归,但病例数量和住院病例数量仍然较高,需要持续监测.
科学领域:
- 流行病学 流行病学
- 病毒学 病毒学
- 公共卫生 公共卫生
背景情况:
- 在COVID-19大流行期间,非药物干预 (NPI) 显著影响了呼吸道病毒传播动态.
- 关于这些流行病学转变及其流行后后果的长期数据有限.
- 了解这些变化对于预测未来的呼吸道疾病负担至关重要.
研究的目的:
- 系统地评估呼吸道病毒循环,季节性,年龄分布和疾病负担的变化.
- 为了比较流行病前,流行病前和流行病后的时期.
- 评估COVID-19大流行对呼吸道感染的长期影响.
主要方法:
- 综合症多重面板测试数据的分析来自83823个呼吸器样本 (56519名患者).
- 数据来自西北瑞士的两个高等保健中心.
- 病毒活动在流行前 (2010-2019),流行 (2019-2022) 和流行后 (2022-2024) 期间的比较.
主要成果:
- 流行性SARS-CoV-2导致流感病毒 (IV),呼吸道同胞病毒 (RSV) 和其他常见的呼吸道病毒的70-90%下降.
- 鼻病毒/肠病毒和腺病毒的影响较小.
- 对IV,RSV和非典型细菌,观察到NPI后提升,显著的季外活动和增加的住院治疗,特别是在儿科患者中.
结论:
- 随着COVID-19大流行,RTI病因,季节性和年龄分布发生了重大变化.
- 缓解NPIs增加了对RTIs的易感性,特别是在儿童中,导致住院率更高.
- 虽然疫情前的模式正在回归,但持续的转变需要持续的监测,以管理不断变化的呼吸道病毒动态.
关键词:
卡尔维 (CARV) 公司根据COVID-19的情况,这就是为什么RSV RSV.在SARS-CoV-2中.不典型的细菌是不典型的细菌社区获得的呼吸道病毒流感 流感 流感 流感 流感多重核酸测试多重核酸测试呼吸道同胞性病毒综合征测试 综合征测试 综合征测试更多相关视频
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