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Updated: Jan 14, 2026

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双重抑制KRASG12D和HSP90对抗KRASG12D抑制剂耐药性是有效的

Inés Pulido1, Laura C Gunder1, Chenghao Ying2

  • 1University of Illinois at Chicago, Chicago, IL, United States.

Molecular cancer therapeutics
|October 23, 2025
PubMed
概括

针对KRASG12D和HSP90的双抑制剂在抗药性癌症方面表现有前途. 这种方法克服了单独使用KRASG12D抑制剂的耐药性,为难以治疗的KRASG12D突变瘤提供了一种新策略.

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