概括
从年轻到中年人的体重增加与中国成年人的高血压和高血压风险有关. 终身控制体重对于降低高血压负担至关重要.
科学领域:
- 心血管健康 心血管健康
- 公共卫生 公共卫生
- 流行病学 流行病学
背景情况:
- 关于亚洲人群体重变化和心血管健康的证据有限.
- 中国HEART项目为研究中国成年人的这种关联提供了有价值的数据集.
研究的目的:
- 为了研究从年轻到中年人的体重变化与血压之间的联系.
- 确定中国成年人体重轨迹与高血压风险之间的关系.
主要方法:
- 利用来自中国HEART项目 (2015-2022) 的数据,包括年龄在35-64岁之间的56,459名参与者.
- 采用多变量调整限制立方线,线性回归和逻辑回归模型.
- 分析标准化测量,包括问卷,体检和实验室数据.
主要成果:
- 除了稳定的正常体重外,所有体重轨迹都与静缩和静缩血压有关.
- 高血压风险随着体重增加显著增加,调整后的几率比率从1.83到4.96.9不等.
- 在不同的体重变化模式中观察到高血压风险的逐渐增加.
结论:
- 成年期体重增加独立预测高血压和高血压.
- 公共卫生倡议应侧重于终身体重管理,以减少人口的高血压负担.
- 研究结果强调了体重控制对于预防中国成年人心血管疾病的重要性.
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