开发和应用一种擦拭采样方法,用于检测医院病房的抗生素表面污染
Carina A Nilsson1, Elizabeth Huynh1, Dallal Rashdan1
1Department of Occupational and Environmental Medicine, Skåne University Hospital, Lund SE-22381, Sweden.
Annals of work exposures and health
|October 23, 2025
概括
在瑞典医院中,抗生素污染很普遍,在大多数表面上都能检测到. 目前的清洁做法不足以防止环境传播,对抗生素耐药性和医疗保健工作者健康构成风险.
科学领域:
- 环境科学环境科学
- 微生物学 微生物学
- 医院卫生 医院卫生
背景情况:
- 医院处理大量的抗生素,用于各种细菌感染.
- 职业暴露和不必要的抗生素使用可能导致细菌耐药性和过敏反应.
研究的目的:
- 开发一项针对抗生素表面污染的擦拭试验.
- 评估瑞典医院的污染水平.
- 提出针对抗生素的卫生指导值.
主要方法:
- 开发了对6种常见抗生素的选擦拭试验方法.
- 利用质谱法进行量化测量.
- 采样了16个医院病房的各种表面类型.
主要成果:
- 在大多数采样表面上检测到抗生素 (例如,cefotaxime 84%, piperacillin 81%).
- 平均污染水平因抗生素和表面类型而异 (地板和储存显示较高水平).
- 封闭系统使用与某些抗生素污染率较低相关.
结论:
- 证实了医院中广泛的抗生素环境污染.
- 对抗生素耐药性和人员健康影响的潜在贡献.
- 不适当的表面清洁程序无法消除泄漏和泄漏.
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