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Updated: Jan 14, 2026

Three-Dimensional Collagen Matrix Scaffold Implantation as a Liver Regeneration Strategy
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使用化学语言模型的架构融合和SAR转移产生了新的肝脏X受体调节器

Nils Christiaan Bandomir1, Tim Hörmann2, Annette Kärcher1

  • 1Institute of Pharmaceutical Chemistry, Goethe University Frankfurt, Max-von-Laue-Strasse 9, 60438 Frankfurt, Germany.

Journal of medicinal chemistry
|October 23, 2025
PubMed
概括

一个化学语言模型为代谢障碍设计了新的肝X受体 (LXR) 调节器. 一个逆LXR激动剂在一种与代谢功能障碍相关的脂肪性肝病模型中显示出有前途的脂解活性.

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