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身体形状指数与成人糖尿病的非线性关联:一个横截面研究
Kaiqi Chen1, Cai Tang2, Yunhua Li3
1Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, China.
PloS one
|October 23, 2025
概括
通过A体形指数 (ABSI) 测量较高的腹部肥胖,与糖尿病风险增加有关. 这种关联在各种人口群体中保持一致,突出显示ABSI是潜在的糖尿病风险指标.
科学领域:
- 内分泌学 在内分泌学.
- 公共卫生 公共卫生
- 肥胖问题研究研究
背景情况:
- 糖尿病是一种全球性健康问题,患病率越来越高.
- 肥胖是2型糖尿病的主要危险因素.
- 像体质指数 (BMI) 这样的传统肥胖指数在反映内脏脂肪方面存在局限性.
研究的目的:
- 为了研究A体形指数 (ABSI) 和糖尿病之间的关联.
- 为了评估ABSI-糖尿病关系在不同人口子组中的稳定性.
- 探索这种关联的非线性性质.
主要方法:
- 使用了来自国家健康和营养检查调查 (NHANES) 的数据.
- 采用多变量线性回归和平滑曲线拟合分析.
- 在性别,种族,高血压和中风史上进行了分层分析.
主要成果:
- 总共有34,693名参与者被分析,其中11.60%患有糖尿病.
- 增加的ABSI与患糖尿病的可能性更高显著相关 (OR = 1.42).
- 观察到一个非线性,反向的L形关系,其断点在ABSI 9.54. 最高的ABSI四分位数显示糖尿病的几率增加了96%.
结论:
- 在较高的ABSI和糖尿病患病率之间存在正相关性.
- 在糖尿病风险方面,ABSI显示出作为肥胖评估的有效替代或补充指标的潜力.
- 这种关联在各个子组中是一致的,除了在有中风病史的个人中.
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