日本男性肥胖指数与认知功能之间的关系:一个横截面研究
Satoshi Matsuno1,2, Yuji Ozeki1, Sayaka Kadowaki3,4
1Department of Psychiatry, Shiga University of Medical Science, Shiga, Japan.
PloS one
|October 23, 2025
概括
内脏 (VAT) 与皮下脂肪组织 (VSR) 的比率可能会影响日本男性的认知功能. 较低的VSR与较差的认知评分有关,这表明脂肪分布是大脑健康的关键.
科学领域:
- 老年学是一门学科.
- 神经科学是一个神经科学.
- 代谢健康 代谢健康
背景情况:
- 肥胖指数和认知功能越来越多地受到研究.
- 脂肪分布,特别是内脏脂肪组织 (VAT) 和皮下脂肪组织 (SAT),可能会影响认知健康.
研究的目的:
- 调查肥胖指数 (VAT,SAT,VAT与SAT比率 - VSR) 与日本男性认知功能之间的关联.
- 确定VSR是否是认知表现的重要预测因素.
主要方法:
- 对776名居住在社区的日本男性进行横截面研究.
- 使用计算机断层扫描测量腹部VAT和SAT.
- 使用认知能力查仪器 (CASI) 评估认知功能.
- 协同变量分析用于比较VSR四分位数中的CASI得分.
主要成果:
- 没有发现认知功能与体重指数,VAT或单独SAT之间的显著关联.
- 与第三个四分位数相比,VSR四分位数最低的参与者显示出明显较低的CASI总分数.
- 低的VSR独立地与认知功能下降有关.
结论:
- 内脏脂肪组织与皮下脂肪组织比率 (VSR) 独立地与中老年和老年日本男性的认知功能有关.
- 在这个人群中,VSR可以作为认知健康的有用指标.
- 脂肪分布,而不仅仅是整体肥胖,对于维持认知功能很重要.
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