关于儿童使用青的家长意识和做法:来自巴基斯坦的横截面研究
Muhammad Saad Nadeem Butt1, Sana Shah2
1Islam Medical College, Sialkot, Pakistan.
PLOS global public health
|October 23, 2025
概括
在巴基斯坦,家长对甲 (乙氨基) 使用和毒性的认识非常低. 大多数家长缺乏足够的知识,增加了儿童中毒的危险,并需要教育干预.
科学领域:
- 药理学 药理学是指药理学的学科.
- 公共卫生 公共卫生
- 儿科 儿科 儿科
背景情况:
- 青是一种广泛使用的止痛药和抗发烧药,可供非处方药 (OTC) 购买.
- 父母对青的使用和儿童中毒性的认识是一个全球性的问题,特别是在巴基斯坦缺乏研究.
- 在资源较低的环境中,与药物相关的毒性对公共卫生构成重大风险.
研究的目的:
- 评估家长对帕拉西他的使用和毒性的认识,在巴基斯坦西阿尔科特市.
- 为了确定与儿童不适当使用青相关的关键公共卫生风险.
- 为政策干预提供信息,以减少与药物有关的毒性.
主要方法:
- 通过从以前的文献中改编的乌尔都语问卷进行了横截面研究.
- 从6个儿科医疗机构的418名家长 (67%的母亲) 收集了数据.
- 用知识分数来评估家长的意识,知识不足被定义为得分低于66.67%.
主要成果:
- 几乎所有参与者都使用了降醇治疗发烧 (99%),而较少的人使用它治疗疼痛 (18%) 或一般疾病症状 (81%).
- 大多数父母都以糖的形式给孩子服用,医疗保健提供者是剂量信息的主要来源.
- 只有32.8%的家长知道过量服用片可能是有害的,75.8%的家长表现出缺乏知识.
结论:
- 巴基斯坦发现,家长对适当使用青醇及其毒性风险的知识严重缺乏.
- 这些发现强调了由于普遍缺乏足够的认识而存在大量的甲中毒风险.
- 教育举措对于提高家长的知识,降低毒性风险和加强对儿童安全的胺注射至关重要.
相关概念视频
Pharmacokinetics in Pediatric Patients: Overview and Drug Absorption
241
Understanding the physiological differences in the pediatric population is crucial for effective pharmacotherapy. Neonates, infants, and children exhibit significant variations in gastric pH, gastric emptying time, intestinal transit time, and biliary function. These variations profoundly affect oral drug absorption, necessitating a nuanced approach to pediatric dosing.Neonates present with a unique physiological profile, having a gastric pH greater than 4 and faster and more irregular gastric...
241
Pharmacokinetics in Pediatric Patients: Drug Metabolism
191
In pediatric care, understanding the nuances of hepatic drug metabolism is crucial, as it significantly differs from that of adults. This divergence is primarily due to the developmental stage of drug-metabolizing enzymes, which affects how medications are processed in the body. In neonates, for instance, the activity of Phase I enzymes—critical for the initial breakdown of drugs—is markedly reduced, functioning at just 20–40% of the levels seen in adults. This reduction poses...
191
Pharmacokinetics in Pediatric Patients: Drug Distribution
251
Drug distribution in the pediatric population exhibits unique challenges and considerations due to the physiological differences between children, particularly neonates and infants, and adults. A crucial aspect of pediatric pharmacology is understanding how these differences impact the pharmacokinetics of various drugs, necessitating age-specific dosing strategies to ensure efficacy and safety.Neonates and infants have a higher total body water content, ~75%–90% of their body weight,...
251
Pharmacokinetics in Pediatric Patients: Drug Excretion
209
In pediatric medicine, understanding the renal function and drug elimination nuances is crucial for administering safe and effective treatments. Newborns, in particular, display markedly slower renal functions than adults, profoundly affecting how drugs are cleared from their bodies. This slower drug clearance requires clinicians to extend the dosing intervals for many medications to prevent drug accumulation and toxicity while ensuring therapeutic efficacy.One key area where these adjustments...
209
Drug Dosing: Infants and Children
250
Pediatric patient dosages diverge from adults due to disparities in body surface area, total body water, and extracellular fluid per kilogram of body weight. The dosing regimen considers the variations in pharmacokinetics and pharmacology across distinct age groups, encompassing preterm newborns, infants, young children, older children, and adolescents. Calculation of pediatric patient doses is predicated on determining body surface area, which exhibits a superior correlation with the child's...
250
Factors Affecting Drug Response: Overview
3.0K
When it comes to infants and young children, they are typically administered smaller doses of medication in comparison to adults. This is primarily because their organ functions still need to fully develop, meaning their bodies are not as efficient at metabolizing or eliminating drugs. Additionally, their blood-brain barrier is more permeable than in adults. As a result, high concentrations of drugs can easily penetrate the central nervous system (CNS), potentially leading to neurological...
3.0K


