与西班牙语人士使用5-MeO-DMT相关的重新激活:流行率,预测因素和情绪价值
A M Ortiz Bernal1, C L Raison1,2,3, R L Lancelotta4
1Department of Human Development and Family Studies, School of Human Ecology, University of Wisconsin-Madison, Madison, WI, USA.
Journal of psychoactive drugs
|October 23, 2025
概括
在使用5-Methoxy-N,N-dimethyltryptamine (5-MeO-DMT) 后,重新激活或"闪回"很常见,通常被认为是积极的. 长时间的计划和减少的认知融合预测了这些迷幻体验.
科学领域:
- 神经科学是一个神经科学.
- 心理药理学 心理药理学
- 心理健康研究 心理健康研究
背景情况:
- 5-Methoxy-N,N-dimethyltryptamine (5-MeO-DMT) 是一种强烈的迷幻化合物,引起了人们对其在心理健康方面的潜在治疗应用的关注.
- 再激活现象,类似于类似于重新激活的现象.
- 在使用-5-MeO-DMT后经常有报道,但仍然不太了解,需要进行系统的调查.
研究的目的:
- 为了确定在5-MeO-DMT给药后发生的反激活的患病率,预测因素和情绪价值.
- 探索人口 (性别),体验 (计划时间,急性影响强度,意义) 和心理 (认知融合) 变量对重新激活发生和感知的影响.
主要方法:
- 采用横截面调查设计,收集了90名西班牙语人士报告使用5-MeO-DMT的数据.
- 进行了描述性统计和多变量后勤回归分析,以确定反激活的预测因素及其情感价值.
主要成果:
- 大多数 (69%) 参与者报告经历过激活,其中大多数 (97%) 描述为积极或中性.
- 多变量分析显示,提前规划的时间较长和认知融合的减少是重新激活事件的显著预测因素.
- 具有挑战性的急性经历与不太积极的重新激活感知相关,而心理洞察力与更积极的感知有关.
结论:
- 再激活是一种常见的5MeO-DMT后现象,在这个队列中主要经历中性或积极.
- 重新激活和减少认知融合之间的关联表明,对幻觉辅助疗法的潜在临床影响.
- 需要进一步的研究来阐明5-MeO-DMT诱导的活性化机制和治疗相关性.
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