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Updated: Jan 14, 2026

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3'-脱氧-β-d-阿皮奥-d-弗拉诺西尔核酸的合成和生物物理特性

Victorio Jauregui-Matos1,2, Dhrubajyoti Datta1, Jayanta Kundu1

  • 1Alnylam Pharmaceuticals, 675 West Kendall, Cambridge, Massachusetts 02142, United States.

ACS chemical biology
|October 23, 2025
PubMed
概括

研究人员合成了称为apioNAs的新型改性核酸构建块. 这些apioNA对DNA/RNA降解具有很高的抗性,从而使潜在的治疗性寡核酸开发成为可能.

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