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Updated: Jan 14, 2026

In Vitro Aggregation Assays Using Hyperphosphorylated Tau Protein
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异常的S293酸化驱动陶的寡合化重复R2:从分子动力学模拟的洞察力

Viet Hoang Man1, Xibing He1, Phuong H Nguyen2

  • 1Department of Pharmaceutical Sciences and Computational Chemical Genomics Screening Center, School of Pharmacy, University of Pittsburgh, Pittsburgh, Pennsylvania 15261, United States.

ACS chemical neuroscience
|October 23, 2025
PubMed
概括

蛋白中S293的异常酸化促进了其聚合,类似于S289. 这一发现对于开发针对寡合化的阿尔茨海默病 (AD) 疗法至关重要.

关键词:
雷姆德 (REMD) 是一个非常危险的疾病.在S293中,S293是S293中的一个.陶重复的重复氧化聚合物的一种.酸化的方法是:光化.模拟模拟是指一个模拟模拟器.

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