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Updated: Jan 14, 2026

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STT3A对于Wnt信号传递至关重要,并且代表了由RNF43缺乏驱动的癌症的标

Zhengjin He1, Shishuang Chen1, Jinlong Suo2

  • 1Key Laboratory of RNA Innovation, Science and Engineering, Shanghai Institute of Biochemistry and Cell Biology, Center for Excellence in Molecular Cell Science, Chinese Academy of Sciences, University of Chinese Academy of Sciences, Shanghai 200031, China.

Cell chemical biology
|October 23, 2025
PubMed
概括

STT3A是Wnt通路的关键调节者,对于缺乏RNF43的癌症至关重要. 抑制STT3A通过影响LRP6糖化来阻止癌症生长,提供了一个新的治疗点.

关键词:
通过LRP6的糖化.缺乏RNF43的癌症在STT3A中.没有信号发送.治疗目标是治疗的目标.

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