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在外周动脉疾病中诊断和治疗四肢缺血的前沿方法
Goodluck Okoro1,2, Fortune K Owunnah3, Catherine C Applegate2
1Department of Bioengineering, University of Illinois at Urbana-Champaign, Urbana, IL, United States of America.
Progress in biomedical engineering (Bristol, England)
|October 23, 2025
概括
周围动脉疾病 (PAD) 和四肢缺血需要早期诊断和干预. 本综述涵盖了最新的诊断工具和治疗方法,包括新兴的再生疗法,以改善患者的治疗结果.
科学领域:
- 血管医学 血管医学
- 再生医学是一种再生医学.
背景情况:
- 周围动脉疾病 (PAD) 是一种普遍的循环状况,导致四肢血流减少.
- 与PAD相关的肢体缺血严重损害生活质量,并增加截肢风险.
研究的目的:
- 为PAD和四肢缺血症提供当前和新兴诊断和治疗策略的全面审查.
- 突出传统和新型治疗方式的进步.
主要方法:
- 对诊断技术的系统审查:脚-手臂指数,双重超声波,MR血管学,CT血管学,分子成像和近红外光谱学.
- 治疗干预措施的分析:药理学药物,内血管程序,基因疗法,干细胞疗法,非热等离子体和细胞外囊泡疗法.
主要成果:
- 有广泛的诊断工具可用,分子成像和光谱学的持续发展.
- 已建立的治疗方法包括抗血小板药物,他类药物,血管造形术和支架.
- 像基因疗法,干细胞,非热等离子体和细胞外囊泡等新的再生方法显示出有前途.
结论:
- 及时诊断和干预对于管理PAD和肢体缺血至关重要.
- 新兴疗法为肢体救援和改善患者治疗结果提供了显著的潜力.
- 解决诊断局限性,治疗障碍和成本是推动患者护理的关键.
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