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Updated: Jan 14, 2026

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通过激活STAT3/BCAT1通路,PTGFRN促进非小细胞肺癌恶性进展,并通过激活STAT3/BCAT1通路重新编程BCAA代谢

Feiye Liu1, Mengjie Li2, Peng Yu3

  • 1Respiratory Department of The Sixth Affiliated Hospital, School of Medicine, South China University of Technology, Fuoshan, Guangdong 528042, China; Oncology Center of The Sixth Affiliated Hospital, School of Medicine, South China University of Technology, Fuoshan, Guangdong 528042, China.

Biochemical pharmacology
|October 23, 2025
PubMed
概括

前列腺素F2受体负调节器 (PTGFRN) 通过增强STAT3/BCAT1信号传递和分支链氨基酸代谢来促进非小细胞肺癌. 沉默PTGFRN可以抑制瘤生长和转移.

关键词:
BCAA的新陈代谢过程非小细胞肺癌是非小细胞肺癌.这是一个PTGFRNN.在STAT3中,我们可以使用STAT3.

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