在轻度认知障碍的老年人中,木材落的神经机械原因:响应启动或运动执行是问题吗?
Jessica Pitts1, Shuaijie Wang1, Tanvi Bhatt2
1Department of Physical Therapy, University of Illinois at Chicago, 1919 W Taylor St, Chicago, IL, 60612, USA.
GeroScience
|October 23, 2025
概括
轻度认知障碍 (OAwMCI) 的老年人经历了延迟的肌肉反应和改变的肌肉协同作用,导致倒下. 这些余额赤字影响着启动和执行反应性步骤.
科学领域:
- 神经科学是一个神经科学.
- 生物力学 生物力学
- 老年学是一门学科.
背景情况:
- 轻度认知障碍 (OAwMCI) 的老年人表现出反应平衡缺陷.
- 这些赤字增加了倒退的风险,称为"木材"的下降,由于推迟的逐步反应.
研究的目的:
- 为了调查木材在OAwMCI中落的神经机械原因.
- 这包括检查推迟肌肉发作的延迟和反应性步进期间改变的肌肉协同作用.
主要方法:
- 36名OAwMCI,38名认知完整的老年人 (CIOA) 和20名年轻人遭受了前置姿势扰乱.
- 电肌图 (EMG) 数据是从关键的腿部肌肉 (两股,横向巨,中侧腹肌,前肌) 中收集的.
- 木材跌落被定义为在干扰开始后430ms内没有启动步骤而跌落.
主要成果:
- 木材跌落仅发生在OAwMCI (36%的OAwMCI).
- 跌倒的OAwMCI (MCI:木材) 与没有跌倒 (MCI:步骤) 的人相比,表现出较低的反应稳定性,更短的步骤长度和更长的步骤启动时间.
- 肌肉损伤:木材参与者在步行四肢肌肉和姿势四肢中部胃膜肌肉中表现出延迟的肌肉发作,肌肉协同招募模式的显著变化 (例如,独特的M4招募,缺席的M6招募).
结论:
- 在OAwMCI中,反应性余额赤字与启动和执行反应性步骤的困难有关.
- 这些缺陷可能源于神经病理和感觉运动处理障碍,影响反应启动和运动命令执行.
- 改变的肌肉协同作用,包括M4的招募和未能招募M6,可能会损害协调的步骤反应和执行恢复步骤的能力.
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