功能性连接模式因自闭症学龄前儿童同时出现的注意力问题而有所不同
Alex Boxberger1,2, Bosi Chen2,3, Lindsay Olson2,4
1Department of Psychology, San Diego State University, San Diego, CA, 92182, USA.
Journal of neurodevelopmental disorders
|October 23, 2025
概括
患有自闭症谱系障碍 (ASD) 的儿童早期注意力问题与发育和大脑连接差异有关. 这些发现强调了对患有自闭症和同时出现的注意力问题的幼儿进行早期干预的需要.
科学领域:
- 神经科学是一个神经科学.
- 发展心理学 发展心理学
- 儿童精神病学 儿童精神病学
背景情况:
- 注意缺陷/多动症 (ADHD) 症状在患有自闭症谱系障碍 (ASD) 的儿童中很常见.
- 这些同时出现的症状与显著的发育挑战和较差的结果有关.
- 了解ASD与同时出现的注意力问题 (AP) 的早期发展轨迹至关重要.
研究的目的:
- 研究ASD和同时发生的AP的幼儿的适应能力,发育结果和大脑功能连接 (FC) 的早期差异.
- 为了将ASD和高AP的儿童与ASD和低AP的儿童进行比较.
主要方法:
- 检查了122名1.5-5岁的儿童,有或没有自闭症.
- 评估了自适应/发展技能,自闭症症状,以及前端对象,突出,语言和默认模式网络的FC.
- 使用了一般线性模型分析.
主要成果:
- 与AP较低的同龄人相比,患有ASD和AP升高的儿童表现出较低的发育和适应能力.
- 在ASD和升高AP的儿童中,在前端对象网络以及前端对象和语言/默认模式网络之间观察到降低FC.
- 两组之间没有发现突出网络FC的显著差异.
结论:
- 与ASD同时发生的AP相关的神经发育和行为差异在生命的很早出现.
- 早期注意力缺失症状与ASD幼儿执行电路中的明显连接模式相关.
- 早期识别和干预ASD同时出现的疾病对于改善结果至关重要.
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