运动和营养对绝经后妇女骨密度的影响 - - 一项系统性审查和元分析
Jie Liu1, Xun Li2, Wenhua Zhang1
1School of Graduate Education, Shandong Sport University, Jinan, 250100, Shandong, China.
Nutrition & metabolism
|October 23, 2025
概括
联合运动和营养干预措施对绝经后妇女的骨矿物质密度 (BMD) 产生积极影响. 然而,目前的证据并不支持对改善骨质疏松症的具体综合策略的普遍建议.
科学领域:
- 老年学是指老年学的学科.
- 骨健康 骨健康 骨健康
- 运动生理学 运动生理学
背景情况:
- 绝经后妇女经历激素波动,导致骨矿物质密度 (BMD) 降低和骨折风险增加.
- 运动和营养干预措施都对 BMD 有积极的影响.
研究的目的:
- 评估运动和营养联合干预措施对绝经后妇女的骨质量损伤的影响.
- 将组合干预与单个营养或运动干预进行比较.
- 确定具体的联合策略来改善BMD.
主要方法:
- 在主要数据库 (PubMed,Embase,Cochrane Library,Web of Science,Google Scholar) 进行系统的文献搜索,直到2025年4月4日.
- 在研究选择和数据提取方面遵循PRISMA指南.
- 使用Cochrane风险偏见工具评估偏见风险;使用GRADE方法评估证据质量;使用Stata 17.0.0分析数据.
主要成果:
- 对24项RCT (2236名女性) 的分析表明,与单独营养相比,联合运动和营养 (EN) 对部部,腰椎和整个部的BMD产生了积极的影响 (N).
- 在相同的解剖部位,在炼和营养 (EN) 与单独营养 (N) 之间没有观察到 BMD 的统计学上显著差异.
- 由于干预方案,种群和样本大小的异质性,子组分析结果有限.
结论:
- 目前的证据不足以建立普遍的,基于证据的建议,具体的联合干预策略,以改善绝经后妇女的BMD.
- 可能需要对标准化协议进行进一步研究,以确定最佳的组合策略.
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