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开发小分子酸盐激酶M2抑制剂的最新进展:2020-2025年

Rudradip Das1, Shailendra Sharma1, Pranav Kumar Ambast1

  • 1Department of Medicinal Chemistry, National Institute of Pharmaceutical Education and Research-Ahmedabad (NIPER-A), Opposite Airforce Station, Gandhinagar, India.

Future medicinal chemistry
|October 24, 2025
PubMed
概括

针对Pyruvate kinase M2 (PKM2) 的小分子抑制剂在治疗癌症和炎症性疾病方面表现有前途. 需要进一步的研究来克服临床翻译方面的挑战,并开发安全,有效的PKM2向疗法.

关键词:
癌症 癌症 癌症 癌症葡萄糖溶解是什么抑制剂 抑制剂 抑制剂酸盐激酶M2的 pyruvate 激酶 M2 的 pyruvate 激酶 M2 的 pyruvate 激酶小分子的小分子.

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