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相关概念视频

Herniated Intervertebral Disc l: Introduction01:29

Herniated Intervertebral Disc l: Introduction

Intervertebral disc herniation refers to the displacement of the nucleus pulposus (the gel-like inner core of the disc) through a tear or weakened area in the annulus fibrosus (the outer fibrous ring). The displaced disc material extends beyond the normal boundaries of the disc space and may compress or irritate nearby spinal nerve roots or, less commonly, the spinal cord.Etiology and Risk FactorsHerniation commonly results from degeneration, in which aging reduces disc hydration and...
Degenerative Disc Disease I: Introduction01:27

Degenerative Disc Disease I: Introduction

Degenerative disc disease is a chronic condition in which intervertebral discs gradually lose structure and function. It is not infectious or autoimmune; rather, it results from age-related biochemical and mechanical changes, influenced by genetic, metabolic, and environmental factors.Structure and Function of DiscsThe spine contains 23 intervertebral discs that absorb load, distribute forces, maintain spacing, and allow flexibility. Each disc consists of a nucleus pulposus, a gel-like core...
Degenerative Disc Disease ll: Pathophysiology01:23

Degenerative Disc Disease ll: Pathophysiology

The symptoms of degenerative disc disease arise from a combination of mechanical compression, vascular compromise, and biochemical inflammation, which together disrupt nerve function and produce pain.Mechanical CompressionDisc degeneration reduces height and elasticity, predisposing to herniation of the nucleus pulposus, a major cause of radicular pain. Herniations may be protrusion (bulging with intact annulus), extrusion (nucleus extends beyond disc but remains connected), or sequestration...

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相关实验视频

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腰椎间盘椎间盘间的关联与脊椎末板的模态变化:基于MRI的研究

Pegah Torabi1, Ghazaleh Jamalipour Soufi1, Ali Hekmatnia1

  • 1Department of Radiology, Isfahan University of Medical Sciences, Isfahan, Iran.

Advanced biomedical research
|October 24, 2025
PubMed
概括

模态变化 (MCs) 与腰椎间盘 (LDH) 有关. 第二种类型的MC最常见,特别是在L5-S1中,在LDH水平,年龄和性别之间发现了显著的相关性.

关键词:
椎间盘退化 椎间盘退化椎间盘间的椎间盘,椎间盘间的椎间盘.腰部疼痛 腰部疼痛 腰部疼痛 腰部疼痛腰部 腰部 腰部 腰部磁共振成像技术的使用脊柱 脊柱 脊柱 脊柱 脊柱

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科学领域:

  • 放射学和成像学 放射学和成像学
  • 脊柱疾病 脊柱疾病
  • 肌肉骨疾病 肌肉骨疾病

背景情况:

  • 腰部疼痛 (LBP) 是一个广泛存在的问题,其来源多样化.
  • 腰椎间盘 (LDH) 和Modic变化 (MCs) 是LBP的常见原因.
  • 了解LDH和MC之间的关系对于有效的LBP管理至关重要.

研究的目的:

  • 在被诊断为腰椎间盘 (LDH) 的患者中确定Modic变化 (MCs) 的频率和特征.
  • 分析MCs,LDH,患者人口统计 (年龄,性别) 和水平之间的关联.

主要方法:

  • 截面分析了254张腰椎MRI扫描,这些扫描来自已确认LDH的患者.
  • 评估MC的存在,类型和位置,以及LDH特征.
  • 统计分析以确定MC,LDH,年龄和性别之间的相关性.

主要成果:

  • 在12.2%的腰椎间盘 (LDH) 患者中,存在模态变化 (MCs).
  • 第二种类型的MC是最普遍的 (71.0%),在L5-S1段经常观察到 (41.9%).
  • 在L1-L2,L2-L3和L3-L4级别的年龄和隙之间,以及性别和L2-L3隙之间发现了显著的关联.

结论:

  • 腰椎间盘 (LDH) 与Modic变化 (MCs) 的发展之间存在显著的相关性,特别是II型.
  • 在L2-L3脊柱水平上,LDH和相关的MCs都有显著的流行.
  • 这些发现强调了在LDH诊断和治疗规划中考虑MC的重要性,建议进一步进行纵向研究.