奥米克斯集成确定了CRIP2作为前列腺癌中olaparib耐药性的关键调解者

Weicheng Tian1,2, Yize Li1,2,3, Haiyin Xiao4

  • 1Guangdong Provincial Key Laboratory of Urology, the First Affiliated Hospital of Guangzhou Medical University, Guangzhou Medical University, Guangzhou, China.

概括

这项研究确定了特定的瘤细胞亚群,在割抵抗性前列腺癌 (CRPC) 中驱动Olaparib耐药性. 开发的风险模型和识别的CRIP2基因为个性化治疗提供了新的策略.

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