门诊呼吸道感染诊断的现有证据和差距:呼吁采取行动
Christen J Arena1,2, Holly M Frost3,4, Park Willis5
1Eugene Applebaum College of Pharmacy and Health Sciences, Wayne State University, Detroit, Michigan, USA.
Open forum infectious diseases
|October 24, 2025
概括
抗菌药物管理计划 (ASP) 需要在门诊环境中扩展. 对上呼吸道感染的快速诊断测试 (RDT) 可以优化抗生素处方并减少不必要的使用,但实施挑战仍然存在.
科学领域:
- 临床微生物学 临床微生物学
- 传染性疾病 传染性疾病
- 公共卫生 公共卫生
背景情况:
- 抗生素管理计划 (ASP) 对于打击抗生素耐药性至关重要,但在门诊环境中代表性不足.
- 上呼吸道感染占门诊抗生素处方的很大一部分 (30%),这表明需要改善管理.
- 在门诊环境中过度处方抗生素有助于抗菌素耐药性.
研究的目的:
- 审查快速诊断测试 (RDT) 在URIs门诊管理中的作用和实施.
- 突出R&DT的潜力,特别是医疗点检测 (POCT) 在优化抗生素处方实践方面的潜力.
- 确定R&DT实施的障碍,并探索在门诊环境中加强抗微生物药物管理的战略.
主要方法:
- 对URIs的门诊R&DT举措的当前文献的审查.
- 分析 RDT 对诊断准确性和处方行为的影响.
- 讨论实施挑战,包括工作流,资源和ASP集成.
主要成果:
- RDT可以促进URI如喉炎的准确诊断,从而实现最佳的处方.
- 成功实施RDT可以显著减少不必要的抗菌素使用.
- 缺乏精简的工作流程和ASP支持不足等障碍妨碍了研发技术的最佳利用.
结论:
- 加强ASP的努力在门诊环境中至关重要,研发与开发技术在管理URI中发挥着关键作用.
- 克服实施障碍对于最大限度地发挥R&DT在减少不必要的抗生素处方方面的好处至关重要.
- 需要进一步的研究来证明RDT对临床结果和门诊URIs处方模式的影响.
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