益智古药片治疗结核相关阻塞性肺病:双盲随机对照试验的协议
Jin Dai1, Yifan Zhang2, Jun Su3,4
1Karamay Integrated Traditional Chinese and Western Medicine Hospital (People's Hospital of Karamay), Xinjiang, China.
Frontiers in pharmacology
|October 24, 2025
概括
这项研究调查了与结核相关的阻塞性肺病 (TOPD) 的Yiqi Gubiao药丸. 随机试验评估其作为TOPD患者潜在的新治疗选择的有效性和安全性.
科学领域:
- 呼吸系统医学 呼吸系统医学
- 药理学 药理学是指药理学的学科.
- 传统中国医药 传统中国医药
背景情况:
- 结核相关阻塞性肺病 (TOPD) 是一种高发病率的呼吸道疾病,具有诊断和管理方面的挑战.
- TOPD显著增加了所有原因的死亡风险.
- 临床前研究表明,药丸对呼吸道疾病具有多重目标的治疗效果.
研究的目的:
- 在TOPD患者中系统评估Yiqi Gubiao药丸的治疗疗效.
- 在TOPD治疗的背景下评估Yiqi Gubiao药丸的安全性.
主要方法:
- 一个前性,双盲,随机对照试验,与1:1分配给Yiqi Gubiao药丸或安慰剂.
- 一个为期12周的治疗方案,包括肺功能测试和生活质量评估.
- 监测传统中医药的症状评分和不良事件,以监测安全性.
主要成果:
- 将收集关于基古比亚奥药在治疗TOPD中的有效性数据.
- 包括不良事件在内的安全数据将被系统监测.
- 将评估生活质量和肺功能变化.
结论:
- 这项试验将为治疗TOPD的Yiqi Gubiao药丸的有效性和安全性提供有价值的数据.
- 积极的研究结果可能会将Yiqi Gubiao Pill作为TOPD患者的新疗法选择.
更多相关视频
相关概念视频
Pulmonary Tuberculosis V
533
Medical management of tuberculosis (TB) patients involves a comprehensive approach that includes diagnosis, treatment, and monitoring. The specific strategies can vary depending on the type of tuberculosis (latent or active), the patient's overall health status, and other considerations.
Latent tuberculosis infection occurs when TB bacteria are present in a person's body, but are not causing illness or symptoms. It is not contagious, and preventive treatment is crucial to avoid the...
Latent tuberculosis infection occurs when TB bacteria are present in a person's body, but are not causing illness or symptoms. It is not contagious, and preventive treatment is crucial to avoid the...
533
Blind Procedures
12.8K
Ideally, the people who observe and record the children’s behavior are unaware of who was assigned to the experimental or control group, in order to control for experimenter bias. Experimenter bias refers to the possibility that a researcher’s expectations might skew the results of the study. Remember, conducting an experiment requires a lot of planning, and the people involved in the research project have a vested interest in supporting their hypotheses. If the observers knew which...
12.8K
Pulmonary Tuberculosis IV
473
Tuberculosis, more commonly referred to as TB, is an infectious disease stemming from Mycobacterium tuberculosis. While it primarily impacts the lungs, TB can also affect other body areas. Given its severity and global impact, timely and accurate diagnosis is crucial for controlling its spread and improving patient outcomes.
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...
473
Blinding
3.8K
Blinding is a commonly used method of not telling participants which treatment a subject is receiving. Blinding is a critical part of a randomized control trial or RCT. It reduces the bias that affects the results. In an RCT, blinding is used in the form of a placebo. A placebo effect occurs when untreated subjects falsely believe they have received the treatment and report improved symptoms. A placebo or a dummy treatment is administered to subjects to negate the bias caused by such an effect.
3.8K
Pulmonary Tuberculosis I
822
Tuberculosis, often called TB, is a contagious illness primarily caused by Mycobacterium tuberculosis. It mainly affects the lung parenchyma but can also impact other body parts.
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
822


