自免疫多腺体综合征2型与赫特尔细胞腺瘤:一种罕见的关联
Shalini S Pandya1, Kush Shah2, Hitesh Chavda3
1Department of Internal Medicine, Sterling Hospitals, Ahmedabad, IND.
Cureus
|October 24, 2025
概括
自免疫多腺体综合征2型 (APS2) 是罕见的,往往是晚诊断. 这一案例突出了与赫特尔细胞腺瘤的独特共发生,强调了对这种罕见内分泌病的诊断警和管理.
科学领域:
- 内分泌学 在内分泌学.
- 在瘤学瘤学.
- 罕见疾病 罕见疾病
背景情况:
- 自免疫多腺综合征2型 (APS2) 是一种罕见的内分泌疾病.
- 它通常涉及一次性上腺功能衰竭和自身免疫性甲状腺炎或1型糖尿病.
- 甲状腺结构异常很少在APS 2中报告.
研究的目的:
- 报告一种罕见的APS 2病例与赫特尔细胞腺瘤 (HCA) 一起发生.
- 强调临床怀疑对于诊断APS的重要性 2.
- 在APS 2的背景下强调HCA的管理.
主要方法:
- 一个44岁的男性的病例介绍,症状暗示上腺功能不全.
- 诊断工作包括激素检测,成像和抗体检测.
- 细针吸收活检和随后的甲状腺切除术,用于赫特尔细胞腺瘤.
主要成果:
- APS 2的诊断证实了原发性上腺功能衰竭和自身免疫性甲状腺炎.
- 赫特尔细胞腺瘤被检测并通过他的病理学证实.
- 患者对激素替代疗法反应良好,经过手术后恢复正常.
结论:
- 这种病例代表了APS2和赫特尔细胞腺瘤之间罕见的关联.
- 高临床怀疑对于早期的APS 2诊断至关重要.
- 由于潜在的恶性瘤,HCA需要组织病理学确认和外科治疗.
相关概念视频
Gastritis-II: Pathophysiology
1.2K
Gastritis is marked by disruption of the mucosal barrier that usually protects the stomach tissue from digestive juices and manifests in acute and chronic forms.
In acute gastritis, the gastric mucosa becomes swollen and red and undergoes superficial erosion. Superficial ulceration may lead to bleeding.
In chronic gastritis, persistent or repeated insults lead to chronic inflammatory changes and, eventually, thinning or atrophy of the gastric tissue.
Gastritis can stem from various causes, each...
In acute gastritis, the gastric mucosa becomes swollen and red and undergoes superficial erosion. Superficial ulceration may lead to bleeding.
In chronic gastritis, persistent or repeated insults lead to chronic inflammatory changes and, eventually, thinning or atrophy of the gastric tissue.
Gastritis can stem from various causes, each...
1.2K
Autoimmune Disorders
1.5K
Autoimmune diseases are a group of disorders in which the body's immune system mistakenly attacks its own cells, tissues, and organs. This results from an overactive immune response against substances and tissues normally present in the body. Let's delve into the concept and mechanism of autoimmune diseases from an immune system point of view, explore different causes and examples of such diseases, and discuss potential solutions.
Concept and Mechanism of Autoimmune Diseases
The immune...
Concept and Mechanism of Autoimmune Diseases
The immune...
1.5K
Pathophysiology of Diabetes
3.1K
Diabetes mellitus is a chronic metabolic disorder characterized by hyperglycemia. The four categories of diabetes are type 1 diabetes, type 2 diabetes, other specific types of diabetes, and gestational diabetes.
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility,...
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility,...
3.1K
What is the Immune System?
126.5K
Overview
126.5K
Adrenal Gland Disorders
2.9K
Adrenal gland disorders manifest when the production of adrenal hormones deviates from the norm, resulting in either excessive or insufficient concentrations.
Adrenal insufficiency, characterized by insufficient cortisol and aldosterone production, leads to conditions like Addison's disease. This disorder, affecting the adrenal cortex, exhibits symptoms such as skin bronzing, dehydration, low blood pressure, fatigue, and weight loss. Congenital adrenal hyperplasia, a genetic ailment causing...
Adrenal insufficiency, characterized by insufficient cortisol and aldosterone production, leads to conditions like Addison's disease. This disorder, affecting the adrenal cortex, exhibits symptoms such as skin bronzing, dehydration, low blood pressure, fatigue, and weight loss. Congenital adrenal hyperplasia, a genetic ailment causing...
2.9K
Inflammatory Bowel Disease II: Crohn's Disease
947
Introduction
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by...
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by...
947


