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评估Ropivacaine灌注的有效性通过一个subgaleal排水用于头骨切割后疼痛:一个随机对照试验

Usha Shukla¹, Urvashi Yadav², Deepika Doneria²

¹Anesthesiology and Critical Care, Uttar Pradesh University of Medical Sciences, Saifai, IND.

|October 24, 2025

概括

与0.1%的罗皮瓦卡因或正常盐溶液相比,通过下水道灌注0.2%的罗皮瓦卡因有效地减少了切术后的疼痛,提供了更长的止痛效果和更少的救援药物的需要.

科学领域:

麻醉学麻醉学
神经外科神经外科
疼痛管理疼痛管理

背景情况:

切除术后的疼痛往往很严重,导致诸如内压力增加和慢性头痛等并发症.
有效的疼痛管理对于切术后的患者康复至关重要.

研究的目的:

评估罗皮瓦卡因通过下排水管灌注的有效性,以减少骨切割后的疼痛.
为了比较不同度的罗皮瓦卡因 (0.1%和0.2%) 与正常盐水的影响.

主要方法:

一项前性,双盲,随机对照性研究,涉及120名接受选择性切割的患者.
患者被随机分为三个组:正常的盐水,0.1%的罗皮瓦卡因或0.2%的罗皮瓦卡因通过下排水.
在24小时内评估了术后疼痛 (数值评分表),止痛持续时间,救援止痛使用和患者满意度.

主要成果:

0.2%的罗皮瓦卡因组在灌注后的多个时间点显示了显著较低的数值评分表得分.
在0.2%的罗皮瓦卡因组 (489.24分钟) 与0.1%的罗皮瓦卡因 (112.7分钟) 和正常盐水 (43.87分钟) 相比,疼痛缓解的持续时间显著延长.
0.2%的罗皮瓦卡因组需要最少的救援止痛药 (103.12毫克).

结论:

单剂量0.2%的罗皮瓦卡因通过下排水灌注可提供优异的骨切除术后疼痛控制.
这种方法提供了更长的止痛时间,并减少了补充缓解疼痛的需要.
0.2%的罗皮瓦卡因比0.1%的罗皮瓦卡因和正常盐水更有效地治疗骨切除术后的疼痛.

关键词:

大脑的流失,大脑的流失.进行了骨切除术 (craniotomy).毒品灌注的灌注毒品灌注切术后的疼痛是什么?罗皮瓦卡因 (ropivacaine) 是一种可怕的药物.

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