高收入国家的急性非酒精营养神经病变 - - 一项系统性审查
Karen Irgens Tanderup Hansen1, Elisabeth Waldemar Grønlund1, Daniel Kondziella1,2
1Department of Neurology, Copenhagen University Hospital - Rigshospitalet.
Danish medical journal
|October 24, 2025
概括
急性营养神经病变,通常是由于维生素缺乏引起的,出现虚弱并模仿吉林巴雷综合征. 早期诊断是预防长期缺陷和避免不必要的治疗的关键.
科学领域:
- 神经学 神经学
- 营养科学 营养科学
- 内部医学 内部医学
背景情况:
- 急性营养神经病变是高收入国家住院的重要原因.
- 了解它们的含义,原因,风险因素和结果对于有效管理至关重要.
研究的目的:
- 确定急性营养神经病变住院患者的特征和结果.
- 确定这些疾病的常见原因,危险因素和临床表现.
主要方法:
- 在PubMed,Cochrane图书馆和Embase进行了系统的文献搜索,寻找自1990年以来发表的非酒精性营养不良神经病变病例.
- 分析了36项涉及83名患者的研究数据.
主要成果:
- 胺缺乏是最常见的原因 (54%),表现为下肢虚弱,低和低/反射.
- 腹腔外科手术 (72%) 是一个主要的风险因素,39%的患者患有韦尼克脑病.
- 轴突多神经病是常见的 (72.3%),51%的患者在一年内取得了良好的结果.
结论:
- 营养神经病变可以模仿轴突的吉林巴雷综合征,需要早期识别.
- 及时诊断和营养补充对于预防持久的神经缺陷和避免IVIG或等离子体合成等不适当的治疗至关重要.
相关概念视频
Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy
635
Various diagnostic tests are employed in the diagnostic process for Inflammatory Bowel Disease (IBD), particularly to differentiate between Crohn's disease and ulcerative colitis.
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the...
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the...
635
Anorexia Nervosa
957
Anorexia nervosa is a complex and severe eating disorder characterized by an intense fear of weight gain, an unrelenting pursuit of thinness, and a distorted body image. It often leads to dangerously low body weight relative to an individual's age and height. This disorder is marked by significant physical and psychological consequences, making it one of the most life-threatening psychiatric illnesses.
Symptoms and Physical Effects
Individuals with anorexia nervosa commonly exhibit extreme...
Symptoms and Physical Effects
Individuals with anorexia nervosa commonly exhibit extreme...
957
Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation
349
Clinical manifestationsPeripheral Arterial Disease (PAD) manifests through a range of symptoms, from the characteristic intermittent claudication to atypical presentations and severe complications in advanced stages. Intermittent claudication, a hallmark symptom of PAD, presents as exercise-induced muscle pain that typically resolves within minutes of rest. This pain is reproducible and stems from inadequate blood flow, leading to the accumulation of lactic acid produced during anaerobic...
349
Overview of Protein Metabolism
3.6K
Proteins are broken down into amino acids during digestion. Unlike fats and carbohydrates, which are stored for later use, proteins are not. Instead, amino acids are either used to produce ATP through oxidation or contribute to the creation of new proteins for the growth and repair of the body. Any surplus amino acids from the diet are converted into glucose or triglycerides rather than excreted.
Amino acids play various roles in the body once they are absorbed into cells. They are restructured...
Amino acids play various roles in the body once they are absorbed into cells. They are restructured...
3.6K
Taste Buds and Receptors
4.6K
Gustation, or the sense of taste, is intrinsically linked to the anatomical structures located on the tongue. This organ's surface, along with the entirety of the oral cavity, is adorned with stratified squamous epithelium. Evident on the tongue are elevated structures known as papillae (singular = papilla), which house the mechanisms for the transduction of gustatory stimuli. Four distinct types of papillae exist, each identified by their unique morphological attributes: the circumvallate,...
4.6K
Alzheimer's Disease: Overview
1.6K
Alzheimer's Disease (AD) is a continually advancing neurodegenerative disorder, distinguished by escalating memory loss, cognitive dysfunction, and dementia. The disease unfolds in three stages: preclinical, mild cognitive impairment (MCI), and dementia. Its onset is insidious, and the progression gradual, with the cause not well explained by other disorders.
The clinical diagnosis of AD hinges on the presence of memory and other cognitive impairments. Biomarkers, such as changes in Aβ...
The clinical diagnosis of AD hinges on the presence of memory and other cognitive impairments. Biomarkers, such as changes in Aβ...
1.6K


