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Updated: May 11, 2026

A High-throughput Automated Platform for the Development of Manufacturing Cell Lines for Protein Therapeutics
07:48

A High-throughput Automated Platform for the Development of Manufacturing Cell Lines for Protein Therapeutics

Published on: September 22, 2011

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一个强大的,高度的,半自动的,在培养中的抗体捕获过渡性CHO平台技术技术平台

Lauren Gebhardt1, Molica Abel1, Jing Zhou1

  • 1BioMedicine Design, Preclinical and Translational Sciences, Pfizer Research and Development, 610 MainStreet, Cambridge, MA 02139, USA.

Antibodies (Basel, Switzerland)
|October 24, 2025
PubMed
概括

抗体发现的进步需要快速,大规模的生产. 一个新的半自动化工作流程可以有效地生成纯化抗体,用于功能查和分子评估.

关键词:
这就是AKTA PureTM.我们的CHO4Tx®基因编码 AmMagTM SA-Plus 的代码在培养中捕获抗体的抗体磁性ProA珠子,可以使用磁性ProA珠.半自动化 半自动化过渡性基因表达 过渡性基因表达

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相关概念视频

Hybridoma Technology01:31

Hybridoma Technology

Hybridoma technology is used for the large-scale production of monoclonal antibodies. Monoclonal antibodies bind to only a single antigenic determinant or epitope. Such antibodies are used in research, diagnostics, and disease therapy. The hybridoma technology established in 1975 by Georges Köhler and Cesar Milstein was awarded the Nobel Prize in Medicine in 1984 for revolutionizing research and therapy.
Hybridoma Selection
Commonly used fusion techniques — electroporation, polyethylene glycol...