6%基乙烯粉在接受重大手术的患者的安全性和有效性:随机对照PHOENICS试验

Wolfgang Buhre¹, Óscar Díaz-Cambronero, Simon Schaefer+35

• ¹From the Department of Anaesthesiology, Division of Vital Functions, University Medical Centre Utrecht Q4.2.300, Utrecht, The Netherlands (WB), Department Anesthesiology, Hospital Universitario y Politécnico la Fe Perioperative Medicine Research, Health Research Institute Hospital la Fe, Valencia, Spain, Faculty of Medicine, Department of Surgery, University of Valencia, Spain (ÓD-C), LMU Klinikum, Ludwig Maximilians-University München, München, Universitätsmedizin Oldenburg, Universitätsklinik für Anästhesiologie, Intensivmedizin, Notfallmedizin und Schmerztherapie, Carl von Ossietzky Universität Oldenburg und Klinikum Oldenburg, Oldenburg, Germany (SS), Department of Anaesthesia and Intensive Care, Oblastni nemocnice Kolin, a.s, Czech Republic (MN), Department of Anesthesiology and Intensive Care, Hospital IMED Valencia, Valencia, Spain (MSD), Jessa Hospital, Hasselt University, Hasselt, Belgium (BS), Hospital Universitario de Gran Canaria Doctor Negrín, Las Palmas, Spain (AR-P), Department of Anaesthesiology and Intensive Care Medicine, University Hospital Carl Gustav Carus Dresden, Technische Universität Dresden, Dresden (TR), Universitätsmedizin Oldenburg, Universitätsklinik für Anästhesiologie, Intensivmedizin, Notfallmedizin und Schmerztherapie, Carl von Ossietzky Universität Oldenburg und Klinikum Oldenburg, Oldenburg, Germany (GR), Department of Anaesthesiology and Intensive Care, Hôpital Européen Georges Pompidou, AP-HP, Paris, Université Paris Cité, INSERM UMR-S1140 "Innovations Thérapeutiques en Hémostase", Paris, France (BC), University Hospital Schleswig-Holstein, Campus Kiel, Kiel, Germany (MG), Maastricht University Medical Center+, Maastricht, the Netherlands (GK), Service d'Anesthésie-Réanimation Saint Eloi, Centre Hospitalier Universitaire de Montpellier, Université, Montpellier, France (SJ), Maastricht University Medical Center+, Maastricht, the Netherlands (DdK), University of Valencia, Valencia, Spain (JB), Department of Anaesthesiology and Intensive Care Medicine, University Hospital Carl Gustav Carus Dresden, Technische Universität Dresden, Dresden, Germany, Department of Intensive Care and Resuscitation, Department of Outcomes Research, Anesthesiology Institute, Cleveland Clinic, Cleveland, Ohio, USA (MGdA), University Hospital Centre Zagreb, Zagreb, Croatia (RB), Department of Anaesthesiology and Intensive Care Medicine, Münster University Hospital, Münster, Germany (TS), Anesthesiology Department, Hospital Clínic de Barcelona, Barcelona, Spain (CFO), Centre for Intensive Care and Perioperative Medicine, Jagiellonian University Medical College, Anesthesia and Intensive Care Department, 5th Military Hospital, Krakow, Poland (WS), Department of Anaesthesia and Intensive Care, Fundeni Clinical Institute, Bucharest, Romania (DT), University Hospital Motol, Prague, Czech Republic (TV), University Hospital Center Sestre Milosrdnice, Zagreb, Croatia (ZG), Department of Anesthesiology, Hospital Universitario y Politécnico la Fe, Perioperative Medicine Research, Health Research Institute Hospital la Fe, Faculty of Medicine, Department of Surgery, University of Valencia (MPA-N), Department Anesthesiology, Hospital Universitario y Politécnico la Fe, Perioperative Medicine Research, Health Research Institute Hospital la Fe, Faculty of Mathematical Sciences, University of Valencia, Valencia, Spain (GM), LMU Klinikum, Ludwig Maximilians-University München, München, Germany (ST), Department Anesthesiology. Hospital Universitario y Politécnico la Fe, Perioperative Medicine Research, Health Research Institute Hospital la Fe, Valencia, Spain (NG-G), Jessa Hospital, Hasselt, Belgium, Hasselt University, Hasselt, Belgium (JV), Department of Anaesthesiology and Intensive Care, Hôpital Européen Georges Pompidou, AP-HP, Paris, Université Paris Cité, INSERM UMR-S1140 "Innovations Thérapeutiques en Hémostase", Paris, France (DZ), Department of Anaesthesiology and Intensive Care Medicine, University Hospital Carl Gustav Carus Dresden, Technische Universität Dresden, Dresden (JW), Medical Scientific Affairs (SS), Medical Scientific Affairs, Hospital Care Division, B. Braun Melsungen AG, Melsungen (SR), BU Pharma & Nutrition, Medical Scientific Affairs, Safety in Clinical Trials & Data Management (CG), BU Pharma & Nutrition, Medical Scientific Affairs, Clinical Operations & Medical Writing (MH), BU Pharma & Nutrition, Global Regulatory Affairs, Regulatory Writing (CJ), BU Pharma & Nutrition, Medical Scientific Affairs, Clinical Operations & Medical Writing, Fresenius Kabi Deutschland GmbH Bad Homburg, Germany (UN), Center for Outcomes Research and Department of Anesthesiology, UTHealth, Houston, Texas, USA (DIS), and BU Pharma & Nutrition, Medical Scientific Affairs, Fresenius Kabi Deutschland GmbH, Bad Homburg, Germany (MW).