确定甲状腺活检的适当性:一项综合临床背景和超声波特征的回顾性研究
Saad Habib1, Gilberto Perez Rodriguez Garcia2, Zhongyue Zhang3
1Division of Endocrinology, Department of Medicine, University of Florida, Gainesville FL 32606, USA.
The Journal of clinical endocrinology and metabolism
|October 24, 2025
概括
将甲状腺结节超声波特征与临床因素相结合,提高了活检的适当性. 这种方法有助于防止不必要的甲状腺活检,并确保及时诊断甲状腺癌.
科学领域:
- 内分泌学 在内分泌学.
- 放射学 放射学是一门学科.
- 在瘤学瘤学.
背景情况:
- 甲状腺结节很普遍,对活检的不当选择可能导致甲状腺癌的过度诊断或延迟诊断.
- 需要一个标准化的框架来评估甲状腺活检的适当性.
研究的目的:
- 为了确定不适当的甲状腺活检的频率.
- 评估一个整合超声波特征和临床因素用于活检决策的框架.
主要方法:
- 在一个单一的学术中心进行横截面研究.
- 成年患者在2016-2023年期间接受第一次甲状腺细针吸收 (FNA) 活检.
- 评估活检的适当性,使用一个分层框架,结合超声波特征和临床因素.
主要成果:
- 在481个甲状腺活检中,80.7%的甲状腺活检根据ACR TI-RADS标准可能是适当的.
- 临床因素将7%的活检从可能不合适重新分类为适当.
- 10%的活检被从适当重新分类为可能/极不适当,因为预期寿命有限.
结论:
- 将超声波发现与临床背景相结合,对于优化甲状腺活检决策至关重要.
- 这种方法支持以患者为中心的护理,并减少不适当的程序.
- 该框架有助于完善甲状腺细针吸收 (FNA) 活检的选择过程.
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