婴儿肠杆菌 (Enterococcus infantis) sp. 在这些情况下. nov.,从患有亚托邦性皮肤炎的婴儿便中分离出来
Chin-Kan Chan1,2, Li-Jyun Tsai1, Misa Otoguro3
1Department of Biotechnology, Ming Chuan University, No. 5, De-Ming Rd., Gui-Shan Township, Taoyuan County 333, Taiwan, ROC.
International journal of systematic and evolutionary microbiology
|October 24, 2025
概括
一种新型的格拉姆阳性细菌,Enterococcus infantis sp. 11月,从患有亚托皮性皮肤炎的婴儿中鉴定出来. 这一发现扩大了对人类健康中的Enterococcus属的理解.
科学领域:
- 微生物学 微生物学
- 细菌学 细菌学是一门学科.
- 基因组学就是基因组学.
背景情况:
- 从一个被诊断患有亚托皮性皮炎 (AD) 的10个月大婴儿身上分离出了一种新型的格拉姆阳性菌菌株AD013-P3T.
- 这种隔离是从便样本中进行的,这表明它可能在婴儿肠道微生物组中发挥作用.
研究的目的:
- 描述和分类新的细菌分离AD013-P3T.
- 要确定该分离物是否代表了 *Enterococcus* 属内的新物种.
主要方法:
- 使用16S rRNA基因序列进行了家族遗传学分析.
- 通过平均核酸标识 (ANI) 和数字DNA-DNA杂交 (dDDH) 进行基因组比较.
- 确定基因组DNA的G+C含量.
主要成果:
- 遗传学分析表明,最接近的亲属是Enterococcus diestrammenae (98.7%) 和Enterococcus asini (97.8%).
- 基因组分析 (ANI 75.4-80.4%,dDDH 22.1%) 从 *E. diestrammenae* JCM 18359T中区分了AD013-P3T菌株.
- 确定G+C的含量为43.5摩尔%.
结论:
- 菌株AD013-P3T在遗传学和表型上与已知的Enterococcus物种有所不同.
- 这些数据支持将AD013-P3T菌株归类为一种新物种,Enterococcus infantis* sp. 在新的一年里.
- 类型菌株是AD013-P3T (=NBRC 117136T=BCRC 81462T) 的.
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