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枝状视网膜静脉封闭中的冠状血管指数变化:对抗VEGF和类固醇植入物的比较分析

Serhat Ermis¹, Ece Ozal², Irem Onal²

¹Department of Ophthalmology, Basaksehir Cam and Sakura City Hospital, University of Health Sciences, 34480, Istanbul, Turkey. serhatermis88@hotmail.com.

International ophthalmology

|October 24, 2025

概括

在12个月的时间里,抗VEGF治疗显著降低了支状视网膜静脉封闭 (BRVO) 眼睛的冠状腺血管度指数 (CVI). 德克萨米他植入物没有改变CVI,这表明CVI可以监测BRVO的抗VEGF疗法的有效性.

科学领域:

眼科医生眼科眼科
视网膜血管疾病视网膜血管疾病
冠状图像成像冠状图像成像

背景情况:

分支视网膜静脉封闭 (BRVO) 是一种常见的视网膜血管疾病.
缺氧是BRVO的主要触发因素,影响胆道血管结构.
评估治疗对胆道血管性的影响对于管理BRVO至关重要.

研究的目的:

评估抗VEGF治疗和甲 (DEX) 植入物对BRVO. choroidal血管结构的影响.
为了比较抗VEGF药物的疗效与DEX植入物在改变胆道参数方面的疗效.
探索胆道血管性指数 (CVI) 作为BRVO的预后指标的潜力.

主要方法:

对眼睛的回顾性分析有时性BRVO,未受影响的眼睛,和健康的对照.
扫描源光学连贯性断层扫描 (SS-OCT) 用于基线和12个月后续的成像.
测量冠状血管度指数 (CVI),冠状血管厚度 (CT) 和中央黄斑厚度 (CMT).

主要成果:

与同伴和对照眼相比,BRVO眼睛最初表现出较低的CVI和CT.
抗VEGF治疗导致CVI在12个月内显著下降 (p=0.014).
在BRVO眼中,DEX植入物没有显著改变CVI (p=0.619).

结论:

治疗方式在BRVO中显著影响胆道血管参数.
与DEX植入物不同,抗VEGF疗法对胸腔血管有可测量的影响.
CVI作为监测BRVO患者抗VEGF治疗反应的有价值的预后指标.

关键词:

合冠状结构是一种合冠状结构.冠状动脉血管度指数冠状动脉血管度指数视网膜分支静脉闭塞视网膜分支静脉闭塞图像二进制化的二进制化

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