皮下带异构:成年人的电临床,放射和预后特征
Merve Melodi Cakar1, Tugba Ozum-Irmak2, Kader Karli-Oguz3
1Department of Neurology, School of Medicine, Hacettepe University, Ankara, Turkey. melodihacioglu@gmail.com.
概括
成年人的皮下带异位 (SBH) 通常呈现为难以治疗的焦点,经常伴有发育迟缓. 综合评估对于诊断和管理这种神经元迁移障碍至关重要.
科学领域:
- 神经学 神经学
- 神经科学是一个神经科学.
- 发病学 (Epileptology) 是一个专业的学科.
背景情况:
- 皮下带异质 (subcortical band heterotopia,简称SBH) 是一种神经元迁移障碍,属于阿吉利亚-帕奇吉利亚谱.
- 成年人呈现和SBH的预后因素仍然定义不佳.
研究的目的:
- 描述患有和SBH的成年人的临床,电生理学,放射学特征和长期结果.
主要方法:
- 对16名在2000年至2024年期间被诊断患有SBH的成年患者的回顾性审查.
- 对人口统计学,史,形形象学,治疗和随访数据的分析.
- 对损伤分布的间接/间接EEG和MRI研究的审查.
主要成果:
- 所有16名患者都幸存下来;发作发作时间范围从6个月到15年,其中44%的发育迟缓.
- 所有患者都患有抗药性;EEG显示焦点 (69%的时间) 或多焦点放电.
- 视频EEG监测显示,在86%的病例中,超时性发作半学;迷走神经刺激在3/4的患者中改善了发作.
结论:
- 成年SBH通常呈现为耐火焦点,常见的发育延迟.
- 包括多式EEG,神经成像和遗传检测在内的全面评估对于诊断和管理至关重要.
关键词:
双层皮质的皮质是双重的是一种病.神经成像是一种神经成像.皮层下带的异构是皮层下带的异构.皮层下层层状异构形态 (subcortical laminar heterotopia) 是一个层状异构形态.更多相关视频
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