一个患有千里亚结核病的患者的双边胆管结核瘤
Tanya Jain1, Sachit Mahajan2, Aishwaraya Kanagaraj2
1Vitreo-retina and Uvea Department, Dr Shroff's Charity Eye Hospital, 5072, Kedarnath Road, Daryaganj, New Delhi, 110002, India. tanyajain_t@yahoo.com.
Journal of ophthalmic inflammation and infection
|October 24, 2025
概括
内抗VEGF治疗与标准治疗相结合,有效地管理了眼结核病 (TB) 颗粒瘤. 这种方法有助于控制炎症并促进千里亚结核病患者的愈合.
科学领域:
- 眼科医生 眼科 眼科
- 传染性疾病 传染性疾病
- 免疫学 免疫学 免疫学
背景情况:
- 冠状腺颗粒瘤是眼结核病 (TB) 的常见症状,表明疾病已经扩散.
- 虽然抗结核治疗 (ATT) 和皮质类固醇是标准的,但大型颗粒瘤可能需要额外的治疗.
- 肠内抗VEGF注射可以成为管理广泛结核颗粒瘤的有价值的辅助.
研究的目的:
- 在患有千里亚结核病的患者中报告双边结核颗粒瘤病例.
- 评估辅助性内抗VEGF治疗在治疗大眼结核颗粒瘤方面的疗效.
主要方法:
- 一个年轻的病例报告,免疫能力强的女性患有千里亚结核病和双边胆道粒瘤.
- 治疗包括标准的ATT,口服类固醇,以及每周在受影响的眼睛内注射贝瓦西祖马布 (抗VEGF) 和莫西素.
- 光学连贯断层扫描 (OCT) 用于监测颗粒瘤大小的变化.
主要成果:
- 这位患者在两只眼睛中呈现出多个结核病颗粒瘤,包括左眼中的一个大型状颗粒瘤.
- 经过每周七次静脉内注射,病变呈现出巩固和痕.
- 海外国家和地区证实,冠状腺颗粒瘤的大小显著下降.
结论:
- 每周静脉注射抗VEGF和莫西弗洛克萨,以及ATT和口服类固醇,成功控制了炎症.
- 这种结合治疗导致结核粒瘤在一个军级结核病患者的巩固和痕.
- 辅助性内抗VEGF提供了一个有前途的治疗选择,用于管理复杂的眼部结核病病例.
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