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Updated: Jan 14, 2026

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可转移元素和DNA甲基化在CpG岛屿和CpG减弱的调节元素形成中的作用

Jueng Soo You1, Steve Pierce2, Gangning Liang3

  • 1Department of Biochemistry, School of Medicine, Konkuk University, Chungju-si 27478, Korea.

Proceedings of the National Academy of Sciences of the United States of America
|October 24, 2025
PubMed
概括

可转移元素 (TE) 可能通过阻止它们的插入来解释CpG岛屿 (CGI) 的持久性. 这种进化压力塑造了脊椎动物的基因组,允许通过DNA甲基化进行动态基因调节.

关键词:
CpG岛屿 (CGI) 是一个岛屿.通过DNA甲基化.转录开始站点 (TSS)可转移的元素 (TEs)

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