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美国成年人饮食铁摄入量与中风之间的关联:一项横截面研究
Haixin Zeng1,2, Qianxin Hu2, Yujie Ji1,2
1Department of Neurosurgery, Wuxi No.2 People's Hospital (Jiangnan University Medical Center), Wuxi, China.
Neurological research
|October 24, 2025
概括
这项研究发现,适度的饮食铁摄入量与美国成年人中风风险降低有关. 在中间铁消耗水平下观察到最佳的神经保护,这表明存在非线性关系.
科学领域:
- 营养科学 营养科学
- 流行病学 流行病学
- 心血管健康 心血管健康
背景情况:
- 饮食中的铁摄入量是人类健康的关键因素.
- 在全球范围内,中风仍然是导致残疾和死亡的主要原因.
- 了解饮食和中风风险之间的关系对于公共健康至关重要.
研究的目的:
- 为了研究饮食铁消耗与美国成年人中风发病率之间的联系.
- 探索铁摄入量与脑血管风险之间的潜在非线性关系.
主要方法:
- 分析了2011-2018年国家健康和营养检查调查 (NHANES) 的数据.
- 评估饮食中铁的摄入量,使用两个24小时的回忆.
- 后勤回归建模和受限制的立方线,以评估中风概率和非线性关联.
主要成果:
- 在5,817名美国成年人中,饮食中的铁摄入量与中风发生率之间发现了显著的相关性.
- 适度的铁摄入量 (12.49-17.76毫克/天) 与摄入量最低的群体相比,与脑血管风险降低35%有关.
- 值效应分析表明,摄入量低于8.09毫克/天的脑血管事件风险降低了17%,这表明较低水平的剂量反应关系.
结论:
- 在美国成年人中,饮食中的铁摄入量和中风可能性之间存在非线性,L形的关联.
- 较高的铁摄入量与中风风险降低相关,特别是那些每天摄入不到8.09毫克的人.
- 需要进一步的前性研究来证实这些发现,并阐明潜在的机制.
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