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Updated: Jan 14, 2026

Generation of Mice Derived from Induced Pluripotent Stem Cells
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鼠标诱导的多能干细胞中的染色体不稳定性:对X和Y积体病的洞察

Marianna Paulis1,2, Paola Rebuzzini3, Lucia Susani1,2

  • 1UOS Milan Unit, Istituto di Ricerca Genetica e Biomedica, CNR, Milan, Italy.

Cytogenetic and genome research
|October 24, 2025
PubMed
概括

像胚胎干细胞 (ES) 一样,小鼠诱导的多能干细胞 (iPS) 可以积累遗传改变. 雌性iPS细胞表现出更高的性染色体不稳定性,特别是额外的X染色体,这是多能干细胞中保留的问题.

关键词:
形积分症是一种形积分症.染色体异常 染色体异常诱导的多能干细胞干细胞性染色体的性别染色体一个X染色体是X染色体.在X染色体转移诱导的多能干细胞中,X染色体转移诱导的多能干细胞.在Y染色体中,Y染色体是

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