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Updated: Jan 14, 2026

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基因素宏H2A1.1的损失会导致脏异常,这是由于营养代谢的变化造成的

René Winkler1, Gemma Comas-Armangué2,3, David Corujo1

  • 1Program of Applied Epigenetics, Program of Myeloid Neoplasms, Josep Carreras Leukaemia Research Institute (IJC), Campus Can Ruti, Badalona, Spain.

Science advances
|October 24, 2025
PubMed
概括

基因素变体 macroH2A1.1 损失通过改变营养代谢,特别是减少脂质氧化和增加糖解,影响脏健康. 一种性饮食逆转了这些效应,突出了宏观H2A1.11.1的作用.

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