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Updated: Jan 14, 2026

Delivery of Modified mRNA in a Myocardial Infarction Mouse Model
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Delivery of Modified mRNA in a Myocardial Infarction Mouse Model

Published on: June 11, 2020

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在PLEKHM2 mRNA解码过程中编程的核糖体框架转移会产生一个构成性活跃的蛋白形,支持心肌功能.

Gary Loughran1, Raffaella De Pace2, Ningyu Ding3,4

  • 1School of Biochemistry and Cell Biology, University College Cork, Cork, Ireland.

Science advances
|October 24, 2025
PubMed
概括

人类基因PLEKHM2中的编程核糖体框架转移允许制造第二种蛋白质. 这种框架转移蛋白对于正常心肌细胞功能至关重要.

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