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Updated: Jan 14, 2026

Using RNA-sequencing to Detect Novel Splice Variants Related to Drug Resistance in In Vitro Cancer Models
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在肝细胞癌中,U2AF2通过与SRSF1合作来调节CCND1拼接变体表达来驱动恶性进展和化疗耐药性

Peng Luo1, Shijie Dai1, Xingyuan Xu1

  • 1State Key Laboratory of Trauma and Chemical Poisoning, Army Medical University, Chongqing 400038, China.

Pathology, research and practice
|October 24, 2025
PubMed
概括

拼接因子U2AF2通过改变mRNA拼接来促进肝细胞癌 (HCC) 的生长和转移. U2AF2还可以预测HCC患者的化疗反应.

关键词:
CCND1 一个人的生活肝细胞癌是肝细胞癌.转移 转移 转移 转移核武器的扩散这就是U2AF2AF2的意思.在mRNA拼接过程中.

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