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Updated: Jan 14, 2026

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伊特拉科纳装载纳米乳液:汉森溶解度和电荷驱动的透和基于GastroPlus的预测体内性能

Afzal Hussain1, Mohammad A Altamimi1, Mudassar Shahid1

  • 1Department of Pharmaceutics, College of Pharmacy, King Saud University, Riyadh 11451, Saudi Arabia.

European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences
|October 24, 2025
PubMed
概括

与传统悬浮剂相比,阴离子纳米乳液显著提高了口服伊特拉科纳 (ITZ) 的吸收. 这项研究利用计算建模和体外数据来预测和确认改善药物透率和治疗系统性真菌感染的疗效.

关键词:
这是一项CLSM研究.基于HSPiP和GastroPlus的预测和模拟这种药物是伊特拉可纳.口服使用的MCNE11纳米乳液.透的配置文件可以通过透.

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