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探索一个框架,以确定医疗器械风险评估中的关注物质队列

Mao-Wen Weng1, Xiaoling Sharlene Dai1, Shaoping Wu1

  • 1Abbott Laboratories Medical Devices, St. Paul, Minnesota, USA.

Regulatory toxicology and pharmacology : RTP
|October 24, 2025
PubMed
概括

确定关注物质 (CoCs) 队列对于医疗器械安全至关重要. 这项研究开发了一个框架,使用癌症风险特异剂量和变异性数据来识别潜在的CoC,改善毒理风险评估.

关键词:
(CRSD) 的工作人员.(CoCs) 的意思是"合作伙伴".(TTC) 的时间.艾姆斯试验的测试癌症风险特定剂量 癌症风险特定剂量关注物质的队列 关注物质的队列突变斜率和医疗器械风险评估毒理学关注的门.

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